Authors
Thomas C Kwee, Taro Takahara, Dow‐Mu Koh, Rutger AJ Nievelstein, Peter R Luijten
Publication date
2008/11
Journal
Journal of Magnetic Resonance Imaging: An Official Journal of the International Society for Magnetic Resonance in Medicine
Volume
28
Issue
5
Pages
1141-1148
Publisher
Wiley Subscription Services, Inc., A Wiley Company
Description
Purpose
To compare and determine the reproducibility of apparent diffusion coefficient (ADC) measurements of the normal liver parenchyma in breathhold, respiratory triggered, and free‐breathing diffusion‐weighted magnetic resonance imaging (DWI).
Materials and Methods
Eleven healthy volunteers underwent three series of DWI. Each DWI series consisted of one breathhold, one respiratory triggered, and two free‐breathing (thick and thin slice acquisition) scans of the liver, at b‐values of 0 and 500 s/mm2. ADCs of the liver parenchyma were compared by using nonparametric tests. Reproducibility was assessed by the Bland–Altman method.
Results
Mean ADCs (in 10−3 mm2/sec) in respiratory triggered DWI (2.07–2.27) were significantly higher than mean ADCs in breathhold DWI (1.57–1.62), thick slice free‐breathing DWI (1.62–1.65), and thin slice free‐breathing DWI (1.57–1.66) (P < 0.005). Ranges of …
Total citations
Scholar articles
TC Kwee, T Takahara, DM Koh, RAJ Nievelstein… - Journal of Magnetic Resonance Imaging: An Official …, 2008